Roger SCHIBLI,Rudolf MOSER,Christina Magdalena MULLER,Simon Mensah AMETAMEY,Cindy Ramona FISCHER,Viola GROEHN
申请号：
US16400736
公开号：
US20190255200A1
申请日:
2019.05.01
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein the 18F isotope is linked via a prosthetic group, more specifically via a prosthetic group having a saccharide group, such as a cyclic mono- or oligosaccharide, preferably based on a pyranoside or furanoside, which is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.
