The solid powder hydrophilic medicine and/or the semi- solid composition which contains the solid powder hydrophilic shape medicine and silicone poly- ether is made to form, the said composition and the said silicone pressure sensitive adhesive or the said solution which contains with the said solvent and the said silicone pressure sensitive adhesive are mixed together next, the said semi- solid composition, in addition to the silicone pressure sensitive adhesive or the solution which contains with the solvent and the silicone pressure sensitive adhesive, this hydrophobic matrix is manufactured by making the hydrophobic matrix form. This hydrophobic matrix, the backing material, typically can be applied by the skin of the person, by the mediation of the dermal patch for medicine continuous control dermal dosage.固形粉末親水性薬剤および/または固形粉末親水性賦形剤ならびにシリコーンポリエーテルを含有する半固形組成物を形成させ、次いで、該半固形組成物を、シリコーン感圧接着剤または溶媒とシリコーン感圧接着剤とを含有する溶液に加え、該組成物ならびに該シリコーン感圧接着剤または該溶媒と該シリコーン感圧接着剤とを含有する該溶液を一緒に混合し、疎水性マトリックスを形成させることにより、本疎水性マトリックスが調製される。本疎水性マトリックスは、基材、典型的にはヒトの肌に、薬剤連続制御経皮投与用経皮パッチの仲介により、適用され得る。
