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BISULFATE OF JANUS KINAZE (JAK) INHIBITOR AND METHOD FOR ITS PREPARATION
专利权人:
发明人:
申请号:
RU2015156142
公开号:
RU2015156142A3
申请日:
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
The present invention relates to a bisulfate of a Janus kinase (JAK) inhibitor and a preparation method therefore. More specifically, the present invention relates to a (3aR,5s,6aS)-N-(3-methoxyl-1,2,4-thiadiazole-5-group)-5-(methyl(7H-pyrrolo[2,3-d] pyrimidine-4-group)amino)hexahydrocyclopenta[c]pyrrole-2(1H)-formamide bisulfate shown in the formula (I), a preparation method therefor, and an application thereof. The bisulfate shown in the formula (I) can be well used as Janus kinase (JAK) inhibitor in clinic work, so as to treat rheumatic or rheumatoid arthritis.
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