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Liposomes comprising polymer-conjugated lipids and related uses
专利权人:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
发明人:
Yedgar, Saul
申请号:
AU2012254842
公开号:
AU2012254842A1
申请日:
2012.05.10
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention provides liposomes comprising a lipid bilayer and a polymer- conjugated lipid, wherein said polymer-conjugated lipid is incorporated into said lipid bilayer. The present invention also provides methods of producing the liposomes as well as a method of delivering a nucleic acid to a subject comprising the step of administering said nucleic acid encapsulated in a mixed liposome, a method for performing diagnostic imaging in a subject, comprising the step of administering a diagnostic agent encapsulated in a mixed liposome, and methods for treating, inhibiting, or suppressing a pathological condition in a subject comprising administering to said subject a mixed liposome.
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