TOWNE, CHRISTOPHER L.,KAPLITT, MICHAEL,DELP, SCOTT,DEISSEROTH, KARL,ANGELEY, DAVID,STAHLER, GREG (DECEASED),ANDERSEN, DAN,LUNDMARK, DAVID C.
申请号：
CA2956707
公开号：
CA2956707A1
申请日:
2015.07.29
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
One embodiment is directed to a system for controllably managing pain in the afferent nervous system of a patient having a targeted tissue structure that has been genetically modified to have light sensitive protein, comprising a light delivery element configured to direct radiation to at least a portion of a targeted tissue structure a light source configured to provide light to the light delivery element and a controller operatively coupled to light source wherein the targeted tissue structure comprises a sensory neuron of the patient and wherein the controller is configured to be automatically operated to illuminate the targeted tissue structure with radiation such that a membrane potential of cells comprising the targeted tissue structure is modulated at least in part due to exposure of the light sensitive protein to the radiation.
