Robert Layne Kruse,Karl-Dimiter Bissig,Stephen M. G. Gottschalk,Thomas C. T. Shum
申请号:
US16334706
公开号:
US20190225673A1
申请日:
2017.09.29
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Embodiments of the disclosure include methods and compositions for treatment of a medical condition related to the liver, including at least viral infections and liver cancer, for example. In specific embodiments, immunotherapies are provided for delivering polynucleotides locally to the liver, wherein the polynucleotides encode particular gene products that include bispecific antibodies, including those that target certain liver antigens, for example.