Alyssa M. Larson,Kevin Love,Alisha K. Weight,Alan Crane,Robert S. Langer,Alexander M. Klibanov
申请号:
US15809602
公开号:
US20180085463A1
申请日:
2017.11.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous or intramuscular injection, rather than by lengthy intravenous infusion. These formulations include low-molecular-weight and/or high-molecular-weight proteins, such as mAbs, and viscosity-reducing ionic liquids.