The invention relates to a biopotential signal acquisition system (100) comprising: an analogue readout unit (10) configured to receive an analogue biopotential signal (BS1) and to extract an analogue measured biopotential signal (BS2) and an analogue reference signal (REF) an ADC unit (20) configured to provide a digital version of the analogue measured biopotential signal (DBS2) and the analogue reference signal (DREF) a first digital filter unit (30) comprising a cascaded integrator-comb filter (32) configured to provide a first digital filtered version (DBS2, DREF) of the digital measured biopotential signal (DBS2) and the reference signal (DREF) and a second digital filter unit (40) configured to calculate a digital motion artifact estimate (MA) based on said first digital filtered version signals (DBS2, DREF). The invention further relates to an electronic device and a method for acquisition of biopotential signals.
