Els Beirnaert;Hilde Adi Pierrette Revets;Hendricus Renerus Jacobus Mattheus Hoogenboom
发明人:
Els Beirnaert,Hilde Adi Pierrette Revets,Hendricus Renerus Jacobus Mattheus Hoogenboom
申请号:
US11587749
公开号:
US08188223B2
申请日:
2006.05.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to amino acid sequences that are capable of binding to serum albumin, which sequences do not significantly reduce or inhibit the binding of serum albumin to FcRn or significantly reduce the half-life of serum albumin. It further relates to proteins and polypeptides comprising or essentially consisting of such amino acid sequences; to nucleic acids that encode such amino acid sequences, proteins or polypeptides; to compositions, and in particular pharmaceutical compositions, that comprise such amino acid sequences, proteins and polypeptides; and to uses of such amino acid sequences, proteins and polypeptides.