Nontherapeutic cosmetic use of 6-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid (I) or its salt as an alleviating agent, is claimed. Nontherapeutic cosmetic use of 6-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid of formula (I) or its salt as an alleviating agent, is claimed. A : benzene ring, optionally substituted by one or more substituents consisting of 1-5C alkyl； and m : 1-12. An independent claim is included for 6-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-hexanoic acid (I) or its salts. [Image] ACTIVITY : Antipruritic； Antiinflammatory； Dermatological； Antipsoriatic； Antiallergic； Antiseborrheic. MECHANISM OF ACTION : Interleukin-1 alpha inhibitor； Interleukin 8 inhibitor； Matrix metalloproteinase-1 inhibitor； Matrix metalloproteinase-3 inhibitor.
