The present invention relates to a novel antimicrobial compound derived from nisin. In particular, the compound is based on an unsubstituted nisin [1-12] structure, wherein the compound has an antimicrobial activity that exceeds the activity of the unsubstituted nisin [1-12] structure.本発明はナイシン由来新規抗微生物性化合物に関する。特に、本化合物は非置換ナイシン[1-12]構造に基づき、ここで前記化合物は非置換ナイシン[1-12]構造の活性を上回る抗微生物活性を有する。