Toshio Kawanami;Muneto Mogi;Robert Sun;Yuki Iwaki;Rajeshri Ganesh Karki;Gary Mark Coppola;Gary Michael Ksander
发明人:
Gary Mark Coppola,Yuki Iwaki,Rajeshri Ganesh Karki,Toshio Kawanami,Gary Michael Ksander,Muneto Mogi,Robert Sun
申请号:
US13490562
公开号:
US09006249B2
申请日:
2012.06.07
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides a compound of formula I′;or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, X and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.