INTELLECT NEUROSCIENCES, INC.;MINDSET BIOPHARMACEUTICALS (USA), INC.
发明人:
申请号:
IL14997602
公开号:
IL149976A
申请日:
2002.06.02
申请国别(地区):
IL
年份:
2012
代理人:
摘要:
The invention provides a chimeric peptide or mixture of chimeric peptides that can be formulated as an immunizing composition and used in a method for immunization of a mammal against an internal peptide cleavage product derived from a precursor or mature protein, for which the peptide cleavage product and the precursor or mature protein are self molecules. The chimeric peptide or peptides have an end-specific B cell epitope from a naturally-occurring internal peptide cleavage product of a precursor or mature protein, as a free N- or C-terminus, fused with or without spacer residues to a T helper cell epitope derived from a living source different from that of the internal peptide cleavage product.