Provided herein are compounds, salts, crystalline forms, and pharmaceutical compositions that are related to thiobutyrate compounds, such as Compound 1 and its salts (such as sodium, potassium, and calcium salt), as well as methods of preparing the same. Also provided herein are methods of using the compounds, salts, crystalline forms, and pharmaceutical compositions for the treatment of diseases or disorders, such as gout and hyperuricemia.本發明提供了與硫代丁酸酯化合物有關的化合物、鹽、結晶形式和藥物組合物,例如化合物1及其鹽(例如鈉、鉀和鈣鹽),以及它們的製備方法。本文還提供了使用所述化合物、鹽、結晶形式和藥物組合物治療疾病或病症(如痛風和高尿酸血症)的方法。