Vincent Lenaerts,Patricia Laure Ouadji-Njiki,Johnatan Bacon,Rachid Ouzerourou,Sonia Gervais,Miloud Rahmouni,Damon Smith
申请号：
US11111996
公开号：
US08487002B2
申请日:
2005.04.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A solid dosage formulation having a core with a pharmacological agent dispersed in a first controlled-release matrix from which release of the agent is relatively slow and a coat formed over the core and having the agent dispersed in a second controlled-release matrix from which release of the agent is relatively fast. The first matrix can be a cross-linked high amylose starch and the second matrix can be a mixture of polyvinyl acetate and polyvinylpyrrolidone.
