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ANTIGENIC COMBINATIONS AGAINST FRANCISELLA BACTERIA AND RELATED NANOLIPOPROTEIN PARTICLES, COMPOSITIONS, METHODS AND SYSTEMS
专利权人:
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC;STC.UNM
发明人:
Nicholas Fischer,Amy Rasley,Terry Wu,Julie Lovchik
申请号:
US16543463
公开号:
US20200108133A1
申请日:
2019.08.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are antigenic combinations and related compositions, methods and systems for immunizing a host from an infection caused by Francisella bacterium. The antigenic combination comprises an antigenic polysaccharide component from a Francisella bacterium capable of triggering a humoral immune response in an individual, a protein antigen component from the Francisella bacterium capable of triggering a cellular immune response in the individual, and an adjuvant, the antigenic Francisella polysaccharide component, the Francisella protein antigen component and the adjuvant are in a suitable amount to immunize an individual against the Francisella bacterium.
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