OLBRICH, Carsten,BUNTE, Thomas,PETERS, Jörg,Trill, Thomas,WINTER, Jonas
申请号:
DK13786255
公开号:
DK2916866T3
申请日:
2013.11.05
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
The present invention relates to stable pharmaceutical compositions which contain polypeptides having at least two antigen-binding domains and are especially suited for subcutaneous administration. The invention provides liquid compositions which minimize the formation of undesired polypeptide aggregates (dimers and/or multimers). The present invention further provides a method for minimizing the aggregation of polypeptides having antigen-binding domains in liquid compositions.