경북대학교 산학협력단;KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
PARK, DONG HO,박동호,PARK, DONG HOKR
申请号:
KR1020140072395
公开号:
KR1020150143190A
申请日:
2014.06.13
申请国别(地区):
KR
年份:
2015
代理人:
摘要:
The present invention relates to a method for screening a PDK inhibitor and to a pharmaceutical composition for preventing or treating retinopathy. The method for screening a PDK inhibitor comprises the steps of: treating a PDK inhibitor candidate material to a retina sample separated from an object with retinopathy, a retina sample with hypoxia, and an animal model with retinopathy; and measuring the expression of ER stress genes or the activity of protein in the retina sample or the animal model treated with the candidate material.본 발명은 PDK 억제제의 스크리닝 방법 및 망막병증의 예방 또는 치료용 약학적 조성물에 관한 것이다.