FIELD: medicine.SUBSTANCE: group of inventions refers to therapy and can be used for treating oropharyngeal candidiasis in an HIV-infected patient. That is ensured by administering the antimycotic preparation fluconazole and Tonsilgon N preparation together. Invention also discloses the use of the Tonsilgon N preparation together with an antimycotic therapy with fluconazole and a combination of fluconazole and the Tonsilgon N preparation.EFFECT: group of inventions enables providing fast and complete elimination of Candida fungi, improving local and general immunity by increasing secretory immunoglobulin A in saliva in an HIV-infected patient.11 cl, 7 dwg, 4 ex