The present invention relates to a method for promoting insulin secretion comprising administering an effective amount of plasminogen to a subject; furthermore, the present invention relates to a medicament for promoting insulin secretion.本發明涉及一種治療糖尿病的新方法,包括給藥糖尿病受試者有效量的纖溶酶原,同時本發明涉及用於治療糖尿病的藥物。