<;P>;PROBLEM TO BE SOLVED: To provide an LDL receptor-synthesis promotor and a cholesterol-lowering agent which are continuously administrable on a daily basis, effective, and highly safe. <;P>;SOLUTION: The LDL receptor-synthesis promotor includes an extract of Ganoderma atrum. As the LDL receptor-synthesis promotor is highly safe, and shows an excellent effect of lowering blood cholesterol, it is useful for a drug, quasi-drug and food intended to prevent and improve arteriosclerosis. <;P>;COPYRIGHT: (C)2010,JPO&INPIT