Roger Schibli,Rudolf Moser,Cristina Magdalena Mueller,Simon Mensah Ametamey,Thomas Betzel,Viola Groehn
申请号：
US14399688
公开号：
US20150125390A1
申请日:
2013.05.08
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention is directed towards new 18F-folate/antifolate analogue radiopharmaceuticals, wherein the phenyl group within folate structures has been replaced by an 18F-heterocycle, their precursors, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.
