Terrance Grant Johns;Frank Furnari;Webster Cavenee;Andrew Scott
发明人:
Terrance Grant Johns,Webster Cavenee,Frank Furnari,Andrew Scott
申请号:
US12450196
公开号:
US09023356B2
申请日:
2008.03.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to the treatment of EGFR-mediated disease, particularly cancer by inhibiting or blocking EGFR and src in combination or simultaneously. The invention relates to treatment, prevention, or modulation of cancer, particularly EGFR-mediated disease, with one or more EGFR modulator and src inhibitor in combination. The invention further relates to the treatment of cancer with anti-EGFR antibodies and src inhibitors. Methods and compositions for treatment of cancer with the antibody anti-EGFR mAb806 in combination or series with a src inhibitor or src inhibitors are described.