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MÉTHODES POUR INDUIRE UNE ANESTHÉSIE
专利权人:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
BROSNAN, ROBERT J.
申请号:
EP13816414
公开号:
EP2872134A4
申请日:
2013.03.14
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides methods for determining the selectivity of an anesthetic for an anesthetic-sensitive receptor by determining the molar water solubility of the anesthetic. The invention further provides methods for modulating the selectivity of an anesthetic for an anesthetic-sensitive receptor by altering or modifying the anesthetic to have higher or lower water solubility. The invention further provides methods of inducing anesthesia in a subject by administering an effective amount of an anesthetic compound identified according to the present methods.
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