THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;NOVARTIS AG
发明人:
申请号：
IL26941219
公开号：
IL269412D0
申请日:
2019.09.17
申请国别(地区):
IL
年份:
2019
代理人:
摘要：
The invention provides compositions and methods improved CAR T cell therapies. Specifically, the invention provides cells with altered expression and/or function of one or more genes, e.g., associated with Tet2, and methods of use therefore. The invention further provides inhibitors of the one or more genes and methods of use therefore in connection with CAR T cells.
