A method of treatment of peripheral arterial disease affecting the limbs (29 figure 2) of a patient comprises the step of applying a therapeutically effective regime of vibration therapy. The invention comprises a vibratory device 10 comprising a motor 16 driving an output shaft on which is mounted an eccentric weight 22 to create vibration of the motor as the shaft rotates. A frame 27 is connected to the motor to which frame the vibrations are transmitted through the connection of the frame to the motor. A pad (110 figure 1) surrounds the frame and into which the vibrations of the frame are transmitted. The pad is applied to the affected limb or limbs of the patient and activated to cause vibrations of the motor to be transmitted through the frame and pad into the tissue of the patent's limb or limbs. The treatment is continued for a therapeutically effective period of time and repeated periodically. Preferably the vibrations act in three orthogonal directions, the frequency being the same in each direction. The amplitude may be the same or different in each direction.
