A bone graft material for the treatment of bone defects and bone neogenesis, which is a material composed of a biodegradable polymer and granules of beta tricalcium phosphate, obtained by the steps of: providing an osteoinductive mixture, which is a dispersion or solution to base of an organic compound having at least one basic non-reactive group containing nitrogen, having a pKa value of 2 to 14, organic compound that is both a dispersing agent and a plasticizer of the biodegradable polymer or copolymer and that can form a salt with a protein having a pKI of 4.0, and a physiologically effective amount of active recombinant human BSP obtained under non-denaturing conditions, where the recombinant human BSP is present in said salt-complex osteoinductive mixture or affinity complex reduced by calcium, hydroxyapatite and complement factor H compared to normal human BSP te in human serum, and, optionally, a pharmaceutically acceptable carrier or excipient； providing an osteoconductive mixture based on granules of tricalcium diphosphate (Ca3 (PO4) 2) in the form of beta crystal, granules that are coated with a biodegradable polymer or copolymer and, optionally, a pharmaceutically acceptable carrier or excipient, osteoconductive mixture that is moldable and conformable, and that hardens quickly in situ when placed by surgery or prosthetic dentistry； and combining said osteoinductive and osteoconductive mixtures to obtain a bone graft material that promotes bone repair and healing of damaged and diseased tissues, and lesions.Un material de injerto óseo para el tratamiento de defectos óseos y la neogénesis ósea, que es un material compuesto de un polímero biodegradable y gránulos de fosfato tricálcico beta, obtenido mediante las etapas de: proporcionar una mezcla osteoinductora, que es una dispersión o solución a base de un compuesto orgánico que tiene al menos un grupo no reactivo básico que contiene nitrógeno, que tiene un valor de pKa de 2 a 14, compuesto orgánico que es
