CAULFIELD, THOMAS J.,CLEMENS, JENNIFER,FRANCIS, ROBERT S.,FREED, BRIAN S.,JOHN, STANLY,LE, TIEU-BINH,PEDGRIFT, BRIAN,RAMOS, ANTONIO D.,ROSSE, GERARD,SMRCINA, MARTIN,THORPE, DAVID S.,WIRE, WILLIAM,ZHAO
申请号：
CA2690001
公开号：
CA2690001C
申请日:
2008.06.04
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to A compound of theformula Ia wherein in any of its stereoisomers forms or a mixtureof stereoisomeric forms in any ratio, or a physiologically acceptablesalt thereof, wherein the substituents are as described herein. Theinventive compounds have CXCR5 inhibitory activity are particularlyuseful in treating or preventing various inflammatory diseases,such as rheumatoid arthritis, multiple sclerosis, lupus, Crohn'sDisease, associated with the modulation of the human CXCR5 receptor.
