Methods for treating or preventing influenza virus infection by administering a serine protease inhibitor

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专利权人:

REGENERON PHARMACEUTICALS INC.

发明人:

PURCELL NGAMBO LISA A.

申请号：

NZ63110513

公开号：

NZ631105A

申请日:

2013.04.15

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

Disclosed is the use of a type II transmembrane serine protease (TTSP) inhibitor in the preparation of a pharmaceutical composition for preventing or reducing the accumulation of influenza-infected alveolar macrophages, influenza-infected neutrophils and/or influenza-infected epithelial cells in the lungs of a subject that has been exposed to or challenged with influenza virus in a subject wherein the TMPRSS2 inhibitor is an antibody or antigen-bending fragment thereof which specifically binds TMPRSS2 and inhibits the protease activity of TMPRSS2 but does not substantially inhibit the protease activity of any other TTSP.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/