Donald E. Champagne,Hitoshi Tsujimoto,Ivo Francischetti,Michael R. Strand,Michail Kotsyfakis
申请号：
US14122300
公开号：
US09365626B2
申请日:
2012.05.25
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention includes a novel protein, also referred to herein as simukunin, that inhibits the function of several physiologically important enzymes. Simukunin is a potent inhibitor of the blood coagulation cascade, inhibiting Factor Xa and functioning as an efficient anticoagulant. Simukunin also inhibits the serine proteases elastase and cathepsin and demonstrates anti-inflammatory properties. Also included are methods of making and using simukunin.
