Kirk J. Leister;Eugene J. Schaefer;Ronald Charles Bates;Elizabeth A. Bramhall;David Michael Didio;Robert Donaldson;Alan R. Flesher;Helen Gray Haggerty;David Henry Kirkley;John Malcolm Tabor;Lee K. Tay
发明人:
Kirk J. Leister,Eugene J. Schaefer,Ronald Charles Bates,Elizabeth A. Bramhall,David Michael Didio,Robert Donaldson,Alan R. Flesher,Helen Gray Haggerty,David Henry Kirkley,John Malcolm Tabor,Lee K. Tay
申请号:
US12086786
公开号:
US10508144B2
申请日:
2006.12.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof. The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.