MURRAY, JAMES ROBERT,KAMIYAMA, FUMIO,WUELFERT, ERNST
申请号：
CA2563830
公开号：
CA2563830C
申请日:
2005.04.28
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Compounds of formula (I) (in which R1； R2, R3 and R4 are the same as ordifferent from each other and each represents an oxo group, a hydroxy group, amercapto group, a hydrogen atom, a halogen atom, an alkoxy group or an aryloxygroup； and the dotted line indicates that there may be a single or dour e bondbetween one of the respective pairs of carbon atoms) and esters thereof can beadministered by transdermal administration. They are particularly effectivewhen applied as a patch, preferably with an adhesive comprising a copolymer offrom 40 to 60% by weight of methoxyethyl acrylate, from 30 to 40% by weight oflauryl acrylate or lauryl methacrylate and from 10 to 25% by weight of a polarmonomer.
