Long, Xiangtian,Dai, Danmei,Brunner, Andreas,Watt, Derek Kevin,Clinch, Keith,Baars, Sylvia Myrna,Dixon, Rachel Anne,Little, Gillian Mary,Landreau, Cyrille Abel Sebastien,Proisy, Nicolas Georges Rene
申请号:
AU2013201061
公开号:
AU2013201061B2
申请日:
2013.02.25
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
#$%^&*AU2013201061B220150402.pdf#####ABSTRACT Provided herein are synthetic methods for preparing a compound of formula (I): 0 HO OH H H H OH N O / HN P=O H2N N N 0 H H H Also provided herein are synthetic methods for preparing a compound of formula (XIII): 0 0 H H H OH N O HN P = N- 0 (XII H2 N =N O H A H The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates of the formula (I) and formula (XIII) compounds. These compounds are useful for treating diseases associated with molybdenum cofactor deficiency.