CHANEL PARFUMS BEAUTE;KYUSHU UNIVERSITY, NAATIONAL UNIVERSITY CORPORATION
发明人:
Masayoshi MIYAMOTO,Yoshihito ODA,Masahiro GOTO
申请号：
US16753396
公开号：
US20200306148A1
申请日:
2018.10.05
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method for producing a nonaqueous composition for external use on the skin including a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dissolved or dispersed in an oil phase, the method including the steps of: dissolving a surfactant in an oil phase to obtain a surfactant solution； mixing the obtained surfactant solution with a strongly hydrophilic amphiphilic solid active ingredient to obtain a suspension； and allowing the obtained suspension to stand still to obtain a transparent composition. Unlike conventional methods for preparing S/O formulations, the strongly hydrophilic amphiphilic solid active ingredient can be solubilized in an oil phase without the process of emulsification and freeze drying.
