The present invention relates to a medicament delivery device comprising a housing, an actuation mechanism (40) arranged inside said housing, the actuation mechanism comprising a plunger rod (42) arranged to act on a stopper (18) of a medicament container (16)； an actuator (84) arranged slidable and connected to the plunger rod (42) for acting on the stopper (18) when said actuator (84) is operated by displacing it in a longitudinal direction of the actuation mechanism (40)； an activator (104) rotatably arranged for activating said actuation mechanism and for setting a dose； said activator (104) comprising a generally tubular activator sleeve (148), said activator sleeve (148) comprises protrusions (150) arranged to interact with ledges (90) on said actuator (84) such that said activator sleeve (148) is rotated when said actuator (84) is operated. The invention is characterised in a first audio generating mechanism comprising audio generating elements (94) and said protrusions (150), which protrusions (150) are arranged to cooperate with said audio generating elements (94) for generating an audible signal after said operation for delivering a dose.
