Giles Albert Brown,Miles Stuart Congreve,Mark Pickworth,Mark Rackham,Benjamin Gerald Tehan
申请号:
US15749743
公开号:
US20180228791A1
申请日:
2016.08.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This invention relates to compounds that are agonists of the muscarinic M4 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1a or a salt thereof, wherein n, p, Q, R1, R2, R3, R9 and R4 are as defined herein.