serine / threonine inhibitors for treatment of hyperproliferative diseases

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专利权人:

ARRAY BIOPHARMA INC.;GENENTECH, INC

发明人:

AIHE ZHOU,HUIFEN CHEN,JACOB SCHWARZ,JIM BLAKE,JOHN GAUDINO,KIRK ROBARGE,LEWIS GAZZARD,MARK CHICARELLI,PETE MOHR,SAM KINTZ

申请号：

BR112015004548

公开号：

BR112015004548A2

申请日:

2013.08.27

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

Compounds having the formula I wherein R2, X and Z as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/