Diane A. BLAKE,Vijay T. John,Ramesh Ayyala,Krzysztof Reiss
申请号：
US14633282
公开号：
US20150209487A1
申请日:
2015.02.27
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The disclosure provides drug delivery devices and methods of making and using the drug delivery devices. The devices include single and multi-layer polymer films made by a breath figure technique having therapeutic agents associated therewith. For example, the devices may be a dual layer polymer film wherein the first layer includes a therapeutic agent incorporated into it by spin coating the first agent with a polymer solution and the second agent is incorporated into the second layer by loading the agent into pores of the second layer after it is spin coated onto the first layer. In some cases one layer provides a burst release and the second layer provides a slow release drug delivery profile. The devices may take on the form of a surgical mesh with a slow release therapeutic drug.
