1.3-Herbal Compounds with BACE 1 and/or BAC2 Inhibitory Activities； Pharmaceutical Components； Preparatory Procedures； Used in the Treatment of Alzheimer's Disease, Diabetes, Arterial Thrombosis, Cancer, Myocardial Infarction and other Diseases.
PINARD EMMANUEL,HILPERT HANS,NARQUIZIAN ROBERT,POLARA ALESSANDRA,ROGERS EVANS MARK,WOLTERING THOMAS,WOSTL WOLFGANG
申请号：
CL2013003262
公开号：
CL2013003262A1
申请日:
2013.11.14
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The present invention provides compounds of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.Compuestos derivados de 1,3-oxazinas, con actividad inhibidora de BACE 1 y/o BACE2； composición farmacéutica que los comprende； procedimiento de preparación； uso en el tratamiento de la Enfermedad de Alzheimer, diabetes, trombosis arterial, cáncer, infarto al miocardio, entre otras patologías.
