Jonathan McKinnon Collins,Joseph Joshua Lambert,Michael John Collins
申请号：
US14944726
公开号：
US09669380B2
申请日:
2015.11.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
An instrument and method for accelerating the solid phase synthesis of peptides are disclosed. The method includes the steps of deprotecting a protected first amino acid linked to a solid phase resin by admixing the protected linked acid with a deprotecting solution in a microwave transparent vessel while irradiating the admixed acid and solution with microwaves, activating a second amino acid, coupling the second amino acid to the first acid while irradiating the composition in the same vessel with microwaves, and cleaving the linked peptide from the solid phase resin by admixing the linked peptide with a cleaving composition in the same vessel while irradiating the composition with microwaves.
