Aleksey V. Kurdyumov,Nathan A. Lockwood,Joram Slager,Dale G. Swan,Robert Hergenrother
申请号:
US12792365
公开号:
US08802121B2
申请日:
2010.06.02
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Silane-functionalized hydrophobic α(1→4)glucopyranose polymers and polymeric matrices are described. Biodegradable matrices can be formed from hydrophobic α(1→4)glucopyranose polymers with reactive pendent silyl ether groups. Reaction of the silyl ether groups provides improved matrix formation through bonding to a device surface of a device, polymer-polymer crosslinking, or both. Biodegradable matrices can be used for the preparation of implantable and injectable medical devices, including those that release a bioactive agent.