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CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS
专利权人:
Janssen Pharmaceutica NV
发明人:
Mark MACIELAG,Raymond J. PATCH,Rui ZHANG,Martin A. CASE,Mark J. WALL,Yue-Mei ZHANG
申请号:
US16344141
公开号:
US20190345214A1
申请日:
2017.10.26
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention comprises compounds of Formula I.wherein:Z4, Z7, Z9, Z11, Z22, Z23, Z26, Z30, Z34, Z35, p, m, n, q, and BRIDGE are defined in the specification. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel compounds are useful for preventing, treating or ameliorating diseases and disorders, such as obesity, type 2 diabetes, the metabolic syndrome, insulin resistance, and dyslipidemia, among others.
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