The invention relates to a process for preparing a composition comprising a bioactive molecule comprising the steps of a. Dissolving a bioactive molecule having at least one acid group with a base at pH=>11 to obtain a solution A b. Neutralizing the solution A with an acid to obtain the composition comprising a bioactive molecule having a pH between 6 and 9, wherein PEG is added before the neutralizing step in case either the base and/or the acid is an inorganic compound, and to a composition comprising a high concentration of natamycin.