Systems and methods for multi-modality data processing are provided. Some embodiments are particularly directed to navigating sets of multi-modality medical data in a multi-modality processing system. In one embodiment, a method for navigating medical data in a medical processing system includes receiving a reference set of medical data by the medical processing system, where the medical data corresponds to a modality selected from the group consisting of: FFR, iFR, pressure, flow, IVUS, and OCT. The medical processing system also receives a navigation command. An enhancement and a subset of the reference set of medical data to enhance are identified based on the navigation command. The medical processing system performs the selected enhancement on the subset of data and the enhanced subset is displayed. The enhancement may include performing a single-axis zoom on the subset.
