CRYSTALINE FORM OF THE COMPOUND PROCESS FOR FORMATION OF THEREOF, USE OF A COMPOUND, METHOD FOR TREATING DISEASES MEDIATED BY GLYCKINASE ACTIVATOR

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专利权人:

ASTRAZENECA AB

发明人:

JAMES MCCABE,GARY PETER TOMKINSON

申请号：

BRPI0721143

公开号：

BRPI0721143A2

申请日:

2007.12.20

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

A novel crystalline form of 3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-[(1-methylethyl)oxy]-N-1H-pyrazol-3-ylbenzamide is described in the specification. This compound is a glucokinase (GLK or GK) activator and useful as a pharmaceutical agent in the treatment or prevention of a disease or medical condition mediated through GLK, leading to a decreased glucose threshold for insulin secretion. Processes for the manufacture of the crystalline form, pharmaceutical compositions comprising the crystalline form and the use of the crystalline form in medical treatment are also described.

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