Karl SCHOENAFINAGER,Henning STEINHAGEN,Bodo SCHEIPER,Uwe HEINELT,Volkmar WEHNER,Matthias HERRMANN,Jacques MAUGER,Pavel SAFAR
申请号:
US13652893
公开号:
US20130040981A1
申请日:
2012.10.16
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The disclosure relates to compounds of formula I:wherein the groups R1, R2, R3, R4, R5 and X are as defined in the disclosure, having antithrombotic activity, which in particular inhibits the protease-activated receptor 1 (PAR1). The disclosure further relates to methods for producing the same and to the use thereof as a pharmaceutical product.