The present invention provides a tooth patch with slowly releasing of whitening agents and use thereof, the tooth patch comprises: (a) a multidirectional elastic nonwoven (b) a hydrogel comprising a tooth whitening agent and (c) a cross-linked network polymer, wherein the tooth patch controls releasing of the tooth whitening agents evenly and slowly.本發明係提供一種具有緩慢釋放美白牙齒物質之牙齒貼片,包含:(a)一多向彈性不織布;(b)一水凝膠,包含一牙齒美白物質;及(c)一網狀交錯聚合物,其中該牙齒貼片控制該牙齒美白物質緩慢且均勻地釋放。100‧‧‧牙齒貼片101‧‧‧多向彈性不織布102‧‧‧水凝膠103‧‧‧網狀交錯聚合物