The present invention aims to provide a production method capable of industrially and producing coenzyme Q10 particles having a high content and superior powder flowability characteristics by simple facility and convenient operations. The present invention provides a method of producing coenzyme Q10 particles, including mixing coenzyme Q10 and a poor solvent by stirring at a temperature not less than the melting point of coenzyme Q10, dispersing coenzyme Q10 into the form of oil droplets, and cooling them to a solidification temperature of coenzyme Q10 or below while stirring the dispersion to give solid particles, wherein the poor solvent is an aqueous solution comprising an organic solvent and/or a surfactant having an HLB of 6 or above. According to the production method of the present invention, coenzyme Q10 particles markedly superior in powder characteristics, and having, for example, a powder flowability index of not less than 80 can be obtained.
