Jules JACOB,Lauren BEACH,Thomas G. WEST,Donald C. MONKHOUSE,Henry L. SURPRENANT
申请号:
US14837354
公开号:
US20150366801A1
申请日:
2015.08.27
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A taste-masked rapidly dispersible dosage form of topiramate is provided. Wax coated particles of topiramate are included within a porous bound matrix. The topiramate retains its taste-masked form after dispersion in the mouth of a subject even though the particles are not coated with a polymeric material. The dosage form disperses in saliva or water in less than 2 min even though it has a high content of wax. It can be used to treat diseases or disorders that are therapeutically responsive to topiramate or a derivative thereof.