A pharmaceutical composition comprising a phenylamidine derivative or a salt thereof, represented by a general formula,wherein R1 and R2 may be same or different, and represent an optionally substituted C3-4alkyl group and one or more agents selected from azole antifungal agents, polyene antifungal agents, candin antifungal agents and fluoropyrimidine antifungal agents, and a method for combination use of the phenylamidine derivative or a salt thereof and the agents are useful for treating fungal infections caused by a fungal pathogen.